Protein Arginine Methyltransferase 1 and 8 Interact with FUS to Modify Its Sub-Cellular Distribution and Toxicity In Vitro and In Vivo

Amyotrophic lateral sclerosis (ALS) is a late onset and progressive motor neuron disease. Mutations in the gene coding for fused in sarcoma/translocated in liposarcoma (FUS) are responsible for some cases of both familial and sporadic forms of ALS. The mechanism through which mutations of FUS result...

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Autors principals: Scaramuzzino, Chiara, Monaghan, John, Milioto, Carmelo, Lanson, Nicholas A., Maltare, Astha, Aggarwal, Tanya, Casci, Ian, Fackelmayer, Frank O., Pennuto, Maria, Pandey, Udai Bhan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631215/
https://ncbi.nlm.nih.gov/pubmed/23620769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061576
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