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Mycobacterium tuberculosis MutT1 (Rv2985) and ADPRase (Rv1700) Proteins Constitute a Two-stage Mechanism of 8-Oxo-dGTP and 8-Oxo-GTP Detoxification and Adenosine to Cytidine Mutation Avoidance

Approximately one third of the world population is infected with Mycobacterium tuberculosis, the causative agent of tuberculosis. A better understanding of the pathogen biology is crucial to develop new tools/strategies to tackle its spread and treatment. In the host macrophages, the pathogen is exp...

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Detalhes bibliográficos
Main Authors: Patil, Aravind Goud G., Sang, Pau Biak, Govindan, Ashwin, Varshney, Umesh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630869/
https://ncbi.nlm.nih.gov/pubmed/23463507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.442566
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