Overexpression of miR-155 causes expansion, arrest in terminal differentiation and functional activation of mouse natural killer cells

It is known that microRNAs (miRs) are involved in lymphocyte development, homeostasis, activation, and occasionally malignant transformation. In this study, a miR-155 transgene (tg) was driven to be overexpressed off of the lck promoter in order to assess its effects on natural killer (NK) cell biol...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Trotta, Rossana, Chen, Li, Costinean, Stefan, Josyula, Srirama, Mundy-Bosse, Bethany L., Ciarlariello, David, Mao, Charlene, Briercheck, Edward L., McConnell, Kathleen K., Mishra, Anjali, Yu, Lianbo, Croce, Carlo M., Caligiuri, Michael A.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2013
Sujets:
Immunobiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630828/
https://ncbi.nlm.nih.gov/pubmed/23422749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-12-467597
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires