Src homology 2 domain–containing inositol-5-phosphatase and CCAAT enhancer-binding protein β are targeted by miR-155 in B cells of Eμ-MiR-155 transgenic mice

We showed that Eμ-MiR-155 transgenic mice develop acute lymphoblastic leukemia/high-grade lymphoma. Most of these leukemias start at approximately 9 months irrespective of the mouse strain. They are preceded by a polyclonal pre–B-cell proliferation, have variable clinical presentation, are transplan...

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Main Authors: Costinean, Stefan, Sandhu, Sukhinder K., Pedersen, Irene M., Tili, Esmerina, Trotta, Rossana, Perrotti, Danilo, Ciarlariello, David, Neviani, Paolo, Harb, Jason, Kauffman, Lauren Rachel, Shidham, Aaditya, Croce, Carlo Maria
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2009
Teme:
Lymphoid Neoplasia
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727407/
https://ncbi.nlm.nih.gov/pubmed/19520806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-05-220814
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