miR-155 targets histone deacetylase 4 (HDAC4) and impairs transcriptional activity of B-cell lymphoma 6 (BCL6) in the Eµ-miR-155 transgenic mouse model

Multiple studies have established that microRNAs (miRNAs) are involved in the initiation and progression of cancer. Notably, miR-155 is one of the most overexpressed miRNAs in several solid and hematological malignancies. Ectopic miR-155 expression in mice B cells (Eμ-miR-155 transgenic mice) has be...

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Detalhes bibliográficos
Main Authors: Sandhu, Sukhinder K., Volinia, Stefano, Costinean, Stefan, Galasso, Marco, Neinast, Reid, Santhanam, Ramasamy, Parthun, Mark R., Perrotti, Danilo, Marcucci, Guido, Garzon, Ramiro, Croce, Carlo M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523868/
https://ncbi.nlm.nih.gov/pubmed/23169640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213764109
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