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All-trans-Retinal Sensitizes Human RPE Cells to Alternative Complement Pathway–Induced Cell Death
PURPOSE. Retinal pigment epithelial (RPE) cell death occurs early in the pathogenesis of age-related macular degeneration (AMD) and Stargardt's disease. Emerging evidence suggests that all-trans-retinal (atRal) and alternative complement pathway (AP) activation contribute to RPE cell death in b...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Association for Research in Vision and Ophthalmology
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3630820/ https://ncbi.nlm.nih.gov/pubmed/23518773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-11020 |
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