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Y-family DNA polymerases and their role in tolerance of cellular DNA damage

The past 15 years have seen an explosion in our understanding of how cells replicate damaged DNA and how this can lead to mutagenesis. The Y-family DNA polymerases lie at the heart of this process, which is commonly known as translesion synthesis. This family of polymerases has unique features that...

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Detalhes bibliográficos
Main Authors: Sale, Julian E., Lehmann, Alan R., Woodgate, Roger
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630503/
https://ncbi.nlm.nih.gov/pubmed/22358330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3289
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