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Y-family DNA polymerases and their role in tolerance of cellular DNA damage

The past 15 years have seen an explosion in our understanding of how cells replicate damaged DNA and how this can lead to mutagenesis. The Y-family DNA polymerases lie at the heart of this process, which is commonly known as translesion synthesis. This family of polymerases has unique features that...

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Bibliografiske detaljer
Main Authors: Sale, Julian E., Lehmann, Alan R., Woodgate, Roger
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630503/
https://ncbi.nlm.nih.gov/pubmed/22358330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3289
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