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Eukaryotic Translesion Polymerases and Their Roles and Regulation in DNA Damage Tolerance

Summary: DNA repair and DNA damage tolerance machineries are crucial to overcome the vast array of DNA damage that a cell encounters during its lifetime. In this review, we summarize the current state of knowledge about the eukaryotic DNA damage tolerance pathway translesion synthesis (TLS), a proce...

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Detalhes bibliográficos
Main Authors: Waters, Lauren S., Minesinger, Brenda K., Wiltrout, Mary Ellen, D'Souza, Sanjay, Woodruff, Rachel V., Walker, Graham C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650891/
https://ncbi.nlm.nih.gov/pubmed/19258535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MMBR.00034-08
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