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Proteasomal Regulation of the Mutagenic Translesion DNA Polymerase, Saccharomyces cerevisiae Rev1
Translesion DNA synthesis (TLS) functions as a tolerance mechanism for DNA damage at a potentially mutagenic cost. Three TLS polymerases (Pols) function to bypass DNA damage in Saccharomyces cerevisiae: Rev1, Pol ζ, a heterodimer of the Rev3 and Rev7 proteins, and Pol η (Rad30). Our lab has shown th...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3034815/ https://ncbi.nlm.nih.gov/pubmed/21227758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.10.008 |
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