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DNA polymerase POLQ and cellular defense against DNA damage
In mammalian cells, POLQ (pol θ) is an unusual specialized DNA polymerase whose in vivo function is under active investigation. POLQ has been implicated by different experiments to play a role in resistance to ionizing radiation and defense against genomic instability, in base excision repair, and i...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3534860/ https://ncbi.nlm.nih.gov/pubmed/23219161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2012.10.004 |
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