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Employing MCMC under the PPL framework to analyze sequence data in large pedigrees
The increased feasibility of whole-genome (or whole-exome) sequencing has led to renewed interest in using family data to find disease mutations. For clinical phenotypes that lend themselves to study in large families, this approach can be particularly effective, because it may be possible to obtain...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3630390/ https://ncbi.nlm.nih.gov/pubmed/23626600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00059 |
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