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Employing MCMC under the PPL framework to analyze sequence data in large pedigrees

The increased feasibility of whole-genome (or whole-exome) sequencing has led to renewed interest in using family data to find disease mutations. For clinical phenotypes that lend themselves to study in large families, this approach can be particularly effective, because it may be possible to obtain...

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Autors principals: Huang, Yungui, Thomas, Alun, Vieland, Veronica J.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630390/
https://ncbi.nlm.nih.gov/pubmed/23626600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00059
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