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Employing MCMC under the PPL framework to analyze sequence data in large pedigrees

The increased feasibility of whole-genome (or whole-exome) sequencing has led to renewed interest in using family data to find disease mutations. For clinical phenotypes that lend themselves to study in large families, this approach can be particularly effective, because it may be possible to obtain...

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Detalles Bibliográficos
Main Authors: Huang, Yungui, Thomas, Alun, Vieland, Veronica J.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630390/
https://ncbi.nlm.nih.gov/pubmed/23626600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00059
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