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pHLIP(®)-Mediated Delivery of PEGylated Liposomes to Cancer Cells

We develop a method for pH-dependent fusion between liposomes and cellular membranes using pHLIP® (pH Low Insertion Peptide), which inserts into lipid bilayer of membrane only at low pH. Previously we establish the molecular mechanism of peptide action and show that pHLIP can target acidic diseased...

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Bibliographic Details
Main Authors: Yao, Lan, Daniels, Jennifer, Wijesinghe, Dayanjali, Andreev, Oleg A., Reshetnyak, Yana K.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630259/
https://ncbi.nlm.nih.gov/pubmed/23416366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.01.037
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