A Comprehensive, Multi-Scale Dynamical Model of ErbB Receptor Signal Transduction in Human Mammary Epithelial Cells

The non-receptor tyrosine kinase Src and receptor tyrosine kinase epidermal growth factor receptor (EGFR/ErbB1) have been established as collaborators in cellular signaling and their combined dysregulation plays key roles in human cancers, including breast cancer. In part due to the complexity of th...

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Autors principals: Helikar, Tomáš, Kochi, Naomi, Kowal, Bryan, Dimri, Manjari, Naramura, Mayumi, Raja, Srikumar M., Band, Vimla, Band, Hamid, Rogers, Jim A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630219/
https://ncbi.nlm.nih.gov/pubmed/23637902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061757
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