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Mammary epithelial cell transformation: insights from cell culture and mouse models

Normal human mammary epithelial cells (HMECs) have a finite life span and do not undergo spontaneous immortalization in culture. Critical to oncogenic transformation is the ability of cells to overcome the senescence checkpoints that define their replicative life span and to multiply indefinitely –...

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Hlavní autoři: Dimri, Goberdhan, Band, Hamid, Band, Vimla
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1175079/
https://ncbi.nlm.nih.gov/pubmed/15987472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1275
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