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Mammary epithelial cell transformation: insights from cell culture and mouse models

Normal human mammary epithelial cells (HMECs) have a finite life span and do not undergo spontaneous immortalization in culture. Critical to oncogenic transformation is the ability of cells to overcome the senescence checkpoints that define their replicative life span and to multiply indefinitely –...

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Bibliografische gegevens
Hoofdauteurs: Dimri, Goberdhan, Band, Hamid, Band, Vimla
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2005
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1175079/
https://ncbi.nlm.nih.gov/pubmed/15987472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1275
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