Загрузка...

Ponatinib suppresses the development of myeloid and lymphoid malignancies associated with FGFR1 abnormalities

Myeloid and lymphoid malignancies associated with FGFR1 abnormalities are characterized by constitutive activated FGFR1 kinase and rapid transformation to acute myeloid leukemia and lymphoblastic lymphoma. Molecular targeted therapies have not been widely used for SCLL. Ponatinib (AP24534), that pot...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Ren, Mingqiang, Qin, Haiyan, Ren, Ruizhe, Cowell, John K.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629706/
https://ncbi.nlm.nih.gov/pubmed/22781593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2012.188
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!