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Dysregulated signaling pathways in the development of CNTRL-FGFR1–induced myeloid and lymphoid malignancies associated with FGFR1 in human and mouse models

Myeloid and lymphoid neoplasm associated with FGFR1 is an aggressive disease, and resistant to all the current chemotherapies. To define the molecular etiology of this disease, we have developed murine models of this disease, in syngeneic hosts as well as in nonobese diabetic/severe combined immunod...

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Autors principals: Ren, Mingqiang, Qin, Haiyan, Kitamura, Eiko, Cowell, John K.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739028/
https://ncbi.nlm.nih.gov/pubmed/23777766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-03-489823
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