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Titanium-mediated reductive cross-coupling reactions of imines with terminal alkynes: An efficient route for the synthesis of stereodefined allylic amines

Low-valency titanium species, generated in situ by using Ti(OiPr)(4)/2 c-C(5)H(9)MgCl reagent, react with imines to give a titanium-imine complex that can couple with terminal alkynes to provide azatitanacyclopentenes with excellent regioselectivity. Stereodefined allylic amines are obtained in good...

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Detalhes bibliográficos
Main Authors: Mao, Kebin, Fan, Guoqin, Liu, Yuanhong, Li, Shi, You, Xu, Liu, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628913/
https://ncbi.nlm.nih.gov/pubmed/23616805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.69
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