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Synthesis of Stereodefined 1,1-Diborylalkenes via Copper-Catalyzed Diboration of Terminal Alkynes

A copper-catalyzed method for the E-selective 1,1-diboration of terminal alkynes is described. The tandem process involves sequential dehydrogenative borylation of the alkyne substrate with HBdan (HBdan = 1,8-diaminonaphthalatoborane), followed by hydroboration with HBpin (HBpin = pinacolborane). Th...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Gao, Yang, Wu, Zhong-Qian, Engle, Keary M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7391966/
https://ncbi.nlm.nih.gov/pubmed/32574499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.0c01901
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