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Resolution of Oligomeric Species during the Aggregation of Aβ(1-40) Using (19)F NMR
In the commonly used nucleation-dependent model of protein aggregation, aggregation proceeds only after a lag phase in which the concentration of energetically unfavorable nuclei reaches a critical value. The formation of oligomeric species prior to aggregation can be difficult to detect by current...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3628624/ https://ncbi.nlm.nih.gov/pubmed/23445400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400027y |
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