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Notch increases the shedding of HB-EGF by ADAM12 to potentiate invadopodia formation in hypoxia

Notch regulates cell–cell contact-dependent signaling and is activated by hypoxia, a microenvironmental condition that promotes cellular invasion during both normal physiology and disease. The mechanisms by which hypoxia and Notch regulate cellular invasion are not fully elucidated. In this paper, w...

詳細記述

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書誌詳細
主要な著者: Díaz, Begoña, Yuen, Angela, Iizuka, Shinji, Higashiyama, Shigeki, Courtneidge, Sara A.
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628517/
https://ncbi.nlm.nih.gov/pubmed/23589494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201209151
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