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Notch increases the shedding of HB-EGF by ADAM12 to potentiate invadopodia formation in hypoxia
Notch regulates cell–cell contact-dependent signaling and is activated by hypoxia, a microenvironmental condition that promotes cellular invasion during both normal physiology and disease. The mechanisms by which hypoxia and Notch regulate cellular invasion are not fully elucidated. In this paper, w...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3628517/ https://ncbi.nlm.nih.gov/pubmed/23589494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201209151 |
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