Class IA PI3-kinase p110β subunit promotes autophagy through Rab5 small GTPase in response to growth factor limitation

Autophagy is an evolutionarily conserved membrane trafficking process. Induction of autophagy in response to nutrient limitation or cellular stress occurs by similar mechanisms in organisms from yeast to mammals. Unlike yeast, metazoan cells rely more on growth factor signaling for a wide variety of...

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Bibliografiske detaljer
Main Authors: Dou, Zhixun, Pan, Ji-An, Dbouk, Hashem A., Ballou, Lisa M., DeLeon, Jennifer L., Fan, Yongjun, Chen, Juei-Suei, Liang, Zhimin, Li, Guangpu, Backer, Jonathan M., Lin, Richard Z., Zong, Wei-Xing
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628298/
https://ncbi.nlm.nih.gov/pubmed/23434372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.01.022
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