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Identification of the Rab5 Binding Site in p110β - Assays for PI3Kβ binding to Rab5

Isoform-specific signaling by Class IA PI 3-kinases depends in part on the interactions between distinct catalytic subunits and upstream regulatory proteins. From among the class IA catalytic subunits (p110α, p110β, and p110δ), p110β has unique properties. Unlike the other family members, p110β dire...

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Bibliographic Details
Published in:Methods Mol Biol
Main Authors: Salamon, Rachel S., Dbouk, Hashem A., Collado, Denise, Lopiccolo, Jaclyn, Bresnick, Anne R., Backer, Jonthan M.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440688/
https://ncbi.nlm.nih.gov/pubmed/25800850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-2569-8_23
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