Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions

Transforming growth factor-β (TGF-β) is involved in vascular formation through activin receptor-like kinase (ALK)1 and ALK5. ALK5, which is expressed ubiquitously, phosphorylates Smad2 and Smad3, whereas endothelial cell (EC)–specific ALK1 activates Smad1 and Smad5. Because ALK5 kinase activity is r...

詳細記述

保存先:
書誌詳細
主要な著者: Itoh, Fumiko, Itoh, Susumu, Adachi, Tomomi, Ichikawa, Kei, Matsumura, Yutaka, Takagi, Takahiro, Festing, Maria, Watanabe, Takuya, Weinstein, Michael, Karlsson, Stefan, Kato, Mitsuyasu
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2012
主題:
Vascular Biology
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628112/
https://ncbi.nlm.nih.gov/pubmed/22498737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-12-395772
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料