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TGF-β Effects on Prostate Cancer Cell Migration and Invasion Are Mediated by PGE(2) through Activation of PI3K/AKT/mTOR Pathway
TGF-β plays an important role in the progression of prostate cancer. It exhibits both tumor suppressor and tumor-promoting activities. Correlations between cyclooxygenase (COX)-2 overexpression and enhanced production of prostaglandin (PG)E(2) have been implicated in cancer progression; however, the...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Endocrine Society
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3628025/ https://ncbi.nlm.nih.gov/pubmed/23515290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-2074 |
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