TGF-β Effects on Prostate Cancer Cell Migration and Invasion Are Mediated by PGE(2) through Activation of PI3K/AKT/mTOR Pathway

TGF-β plays an important role in the progression of prostate cancer. It exhibits both tumor suppressor and tumor-promoting activities. Correlations between cyclooxygenase (COX)-2 overexpression and enhanced production of prostaglandin (PG)E(2) have been implicated in cancer progression; however, the...

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Bibliografiske detaljer
Main Authors: Vo, BaoHan T., Morton, Derrick, Komaragiri, Shravan, Millena, Ana C., Leath, Chelesie, Khan, Shafiq A.
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2013
Fag:
Growth Factors-Cytokines
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628025/
https://ncbi.nlm.nih.gov/pubmed/23515290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-2074
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