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Permeation and block of TRPV1 channels by the cationic lidocaine derivative QX-314
QX-314 (N-ethyl-lidocaine) is a cationic lidocaine derivative that blocks voltage-dependent sodium channels when applied internally to axons or neuronal cell bodies. Coapplication of external QX-314 with the transient receptor potential vanilloid 1 protein (TRPV1) agonist capsaicin produces long-las...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3628012/ https://ncbi.nlm.nih.gov/pubmed/23303863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00012.2013 |
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