Staphylococcus aureus produces pain through pore-forming toxins and neuronal TRPV1 that is silenced by QX-314

The hallmark of many bacterial infections is pain. The underlying mechanisms of pain during live pathogen invasion are not well understood. Here, we elucidate key molecular mechanisms of pain produced during live methicillin-resistant Staphylococcus aureus (MRSA) infection. We show that spontaneous...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Blake, Kimbria J., Baral, Pankaj, Voisin, Tiphaine, Lubkin, Ashira, Pinho-Ribeiro, Felipe Almeida, Adams, Kelsey L., Roberson, David P., Ma, Yuxin C., Otto, Michael, Woolf, Clifford J., Torres, Victor J., Chiu, Isaac M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750211/
https://ncbi.nlm.nih.gov/pubmed/29295977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02448-6
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