Staphylococcus aureus produces pain through pore-forming toxins and neuronal TRPV1 that is silenced by QX-314

The hallmark of many bacterial infections is pain. The underlying mechanisms of pain during live pathogen invasion are not well understood. Here, we elucidate key molecular mechanisms of pain produced during live methicillin-resistant Staphylococcus aureus (MRSA) infection. We show that spontaneous...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Blake, Kimbria J., Baral, Pankaj, Voisin, Tiphaine, Lubkin, Ashira, Pinho-Ribeiro, Felipe Almeida, Adams, Kelsey L., Roberson, David P., Ma, Yuxin C., Otto, Michael, Woolf, Clifford J., Torres, Victor J., Chiu, Isaac M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750211/
https://ncbi.nlm.nih.gov/pubmed/29295977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02448-6
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