Synthesis of (S)-FTY720 vinylphosphonate analogues and evaluation of their potential as sphingosine kinase 1 inhibitors and activators

অনুরূপ উপাদানগুলি

• Synthesis of selective inhibitors of sphingosine kinase 1
  অনুযায়ী: Baek, Dong Jae, অন্যান্য
  প্রকাশিত: (2013)
• Novel sphingosine-containing analogues selectively inhibit sphingosine kinase (SK) isozymes, induce SK1 proteasomal degradation and reduce DNA synthesis in human pulmonary arterial smooth muscle cells
  অনুযায়ী: Byun, Hoe-Sup, অন্যান্য
  প্রকাশিত: (2013)
• (S)-FTY720-Vinylphosphonate, an Analogue of the Immunosuppressive Agent FTY720, Is a Pan-antagonist of Sphingosine 1-Phosphate GPCR Signaling and Inhibits Autotaxin Activity
  অনুযায়ী: Valentine, William J., অন্যান্য
  প্রকাশিত: (2010)
• FTY720 and (S)-FTY720 vinylphosphonate inhibit sphingosine kinase 1 and promote its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer and androgen-independent prostate cancer cells
  অনুযায়ী: Tonelli, Francesca, অন্যান্য
  প্রকাশিত: (2010)
• FTY720 Analogues as Sphingosine Kinase 1 Inhibitors: ENZYME INHIBITION KINETICS, ALLOSTERISM, PROTEASOMAL DEGRADATION, AND ACTIN REARRANGEMENT IN MCF-7 BREAST CANCER CELLS
  অনুযায়ী: Lim, Keng G., অন্যান্য
  প্রকাশিত: (2011)