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Indomethacin Promotes Adipogenesis of Mesenchymal Stem Cells Through a Cyclooxygenase Independent Mechanism

Regulation of mesenchymal stem cell (MSC) lineage selection is important for the generation of bone mass. Inhibition of cyclooxygenase-2 (COX2) may increase adipogenesis at the cost of decreasing osteoprogenitor output. Here we investigated the role of COX2 and its products during MSC differentiatio...

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Détails bibliographiques
Auteurs principaux: Styner, Maya, Sen, Buer, Xie, Zhihui, Case, Natasha, Rubin, Janet
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627539/
https://ncbi.nlm.nih.gov/pubmed/20672310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22793
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