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Mechanical Signal Influence on Mesenchymal Stem Cell Fate is Enhanced by Incorporation of Refractory Periods into the Loading Regimen

Mechanical signals of both low and high intensity are inhibitory to fat and anabolic to bone in vivo, and have been shown to directly affect mesenchymal stem cell pools from which fat and bone precursors emerge. To identify an idealized mechanical regimen which can regulate MSC fate, low intensity v...

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Détails bibliographiques
Auteurs principaux: Sen, Buer, Xie, Zhihui, Case, Natasha, Styner, Maya, Rubin, Clinton T, Rubin, Janet
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042527/
https://ncbi.nlm.nih.gov/pubmed/21130997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiomech.2010.11.022
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