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Mechanical Signal Influence on Mesenchymal Stem Cell Fate is Enhanced by Incorporation of Refractory Periods into the Loading Regimen

Mechanical signals of both low and high intensity are inhibitory to fat and anabolic to bone in vivo, and have been shown to directly affect mesenchymal stem cell pools from which fat and bone precursors emerge. To identify an idealized mechanical regimen which can regulate MSC fate, low intensity v...

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Bibliographische Detailangaben
Hauptverfasser: Sen, Buer, Xie, Zhihui, Case, Natasha, Styner, Maya, Rubin, Clinton T, Rubin, Janet
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042527/
https://ncbi.nlm.nih.gov/pubmed/21130997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiomech.2010.11.022
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