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Inhibitors of HIV-1 Reverse Transcriptase—Associated Ribonuclease H Activity
HIV-1 enzyme reverse transcriptase (RT) is a major target for antiviral drug development, with over half of current FDA-approved therapeutics against HIV infection targeting the DNA polymerase activity of this enzyme. HIV-1 RT is a multifunctional enzyme that has RNA and DNA dependent polymerase act...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3627382/ https://ncbi.nlm.nih.gov/pubmed/23599900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology1030521 |
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