Usefulness of a selective neutrophil elastase inhibitor, sivelestat, in acute lung injury patients with sepsis

BACKGROUND: Neutrophil elastase plays a crucial role in the development of acute lung injury (ALI) in patients with systemic inflammatory response syndrome (SIRS). The clinical efficacy of the neutrophil elastase inhibitor, sivelestat, for patients with ALI associated with SIRS has not been convinci...

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Bibliografische gegevens
Hoofdauteurs: Miyoshi, Seigo, Hamada, Hironobu, Ito, Ryoji, Katayama, Hitoshi, Irifune, Kazunori, Suwaki, Toshimitsu, Nakanishi, Norihiko, Kanematsu, Takanori, Dote, Kentaro, Aibiki, Mayuki, Okura, Takafumi, Higaki, Jitsuo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Dove Medical Press 2013
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627345/
https://ncbi.nlm.nih.gov/pubmed/23596346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S42004
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