Antitumor activity of MEK and PI3K inhibitors against malignant pleural mesothelioma cells in vitro and in vivo

Malignant pleural mesothelioma (MPM) is an aggressive malignancy for which there is no approved targeted therapy. We examined the therapeutic efficacy of the mitogen-activated protein kinase kinase (MEK) and phosphatidylinositol 3-kinase (PI3K) inhibitors against human MPM cell lines both in vitro a...

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Detalhes bibliográficos
Main Authors: MIYOSHI, SEIGO, HAMADA, HIRONOBU, HAMAGUCHI, NAOHIKO, KATO, AKI, KATAYAMA, HITOSHI, IRIFUNE, KAZUNORI, ITO, RYOJI, MIYAZAKI, TATSUHIKO, OKURA, TAKAFUMI, HIGAKI, JITSUO
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582904/
https://ncbi.nlm.nih.gov/pubmed/22580933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2012.1462
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