Usefulness of a selective neutrophil elastase inhibitor, sivelestat, in acute lung injury patients with sepsis

BACKGROUND: Neutrophil elastase plays a crucial role in the development of acute lung injury (ALI) in patients with systemic inflammatory response syndrome (SIRS). The clinical efficacy of the neutrophil elastase inhibitor, sivelestat, for patients with ALI associated with SIRS has not been convinci...

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Bibliografske podrobnosti
Main Authors: Miyoshi, Seigo, Hamada, Hironobu, Ito, Ryoji, Katayama, Hitoshi, Irifune, Kazunori, Suwaki, Toshimitsu, Nakanishi, Norihiko, Kanematsu, Takanori, Dote, Kentaro, Aibiki, Mayuki, Okura, Takafumi, Higaki, Jitsuo
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2013
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627345/
https://ncbi.nlm.nih.gov/pubmed/23596346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S42004
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