Usefulness of a selective neutrophil elastase inhibitor, sivelestat, in acute lung injury patients with sepsis

BACKGROUND: Neutrophil elastase plays a crucial role in the development of acute lung injury (ALI) in patients with systemic inflammatory response syndrome (SIRS). The clinical efficacy of the neutrophil elastase inhibitor, sivelestat, for patients with ALI associated with SIRS has not been convinci...

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Detalhes bibliográficos
Main Authors: Miyoshi, Seigo, Hamada, Hironobu, Ito, Ryoji, Katayama, Hitoshi, Irifune, Kazunori, Suwaki, Toshimitsu, Nakanishi, Norihiko, Kanematsu, Takanori, Dote, Kentaro, Aibiki, Mayuki, Okura, Takafumi, Higaki, Jitsuo
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627345/
https://ncbi.nlm.nih.gov/pubmed/23596346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S42004
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