Usefulness of a selective neutrophil elastase inhibitor, sivelestat, in acute lung injury patients with sepsis

BACKGROUND: Neutrophil elastase plays a crucial role in the development of acute lung injury (ALI) in patients with systemic inflammatory response syndrome (SIRS). The clinical efficacy of the neutrophil elastase inhibitor, sivelestat, for patients with ALI associated with SIRS has not been convinci...

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Detalles Bibliográficos
Autores principales: Miyoshi, Seigo, Hamada, Hironobu, Ito, Ryoji, Katayama, Hitoshi, Irifune, Kazunori, Suwaki, Toshimitsu, Nakanishi, Norihiko, Kanematsu, Takanori, Dote, Kentaro, Aibiki, Mayuki, Okura, Takafumi, Higaki, Jitsuo
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627345/
https://ncbi.nlm.nih.gov/pubmed/23596346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S42004
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