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STAT1 is required for IL-6 mediated Bcl6 induction for early Tfh differentiation

Bcl6 is required for CD4 T cell differentiation into follicular helper cells (Tfh). Here, we examined the role of IL-6 in early processes of in vivo Tfh differentiation, as the timing and mechanism of action of IL-6 in Tfh cell differentiation has been controversial in vivo. We found that early Bcl6...

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Main Authors: Choi, Youn Soo, Eto, Danelle, Yang, Jessica A., Lao, Christopher, Crotty, Shane
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626564/
https://ncbi.nlm.nih.gov/pubmed/23447690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1203032
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