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Nuclear Atrophy of Retinal Ganglion Cells Precedes the Bax-Dependent Stage of Apoptosis

PURPOSE. Retinal ganglion cells atrophy during the execution of the intrinsic apoptotic program. This process, which has been termed the apoptotic volume decrease (AVD) in other cell types, has not been well-characterized in ganglion cells. METHODS. Acute optic nerve crush was used to examine neuron...

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Auteurs principaux: Janssen, Katherine T., Mac Nair, Caitlin E., Dietz, Joel A., Schlamp, Cassandra L., Nickells, Robert W.
Format: Artigo
Langue:Inglês
Publié: The Association for Research in Vision and Ophthalmology 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626519/
https://ncbi.nlm.nih.gov/pubmed/23422829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-9310
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