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Progressive ganglion cell loss and optic nerve degeneration in DBA/2J mice is variable and asymmetric

BACKGROUND: Glaucoma is a chronic neurodegenerative disease of the retina, characterized by the degeneration of axons in the optic nerve and retinal ganglion cell apoptosis. DBA/2J inbred mice develop chronic hereditary glaucoma and are an important model system to study the molecular mechanisms und...

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Detalhes bibliográficos
Main Authors: Schlamp, Cassandra L, Li, Yan, Dietz, Joel A, Janssen, Katherine T, Nickells, Robert W
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1621073/
https://ncbi.nlm.nih.gov/pubmed/17018142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-7-66
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