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Role of HDACs in optic nerve damage-induced nuclear atrophy of retinal ganglion cells

Optic neuropathies are characterized by retinal ganglion cell (RGC) death, resulting in the loss of vision. In glaucoma, the most common optic neuropathy, RGC death is initiated by axonal damage, and can be modeled by inducing acute axonal trauma through procedures such as optic nerve crush (ONC) or...

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Veröffentlicht in:Neurosci Lett
Hauptverfasser: Schmitt, Heather M., Schlamp, Cassandra L., Nickells, Robert W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125391/
https://ncbi.nlm.nih.gov/pubmed/26733303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2015.12.012
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