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Nuclear Atrophy of Retinal Ganglion Cells Precedes the Bax-Dependent Stage of Apoptosis

PURPOSE. Retinal ganglion cells atrophy during the execution of the intrinsic apoptotic program. This process, which has been termed the apoptotic volume decrease (AVD) in other cell types, has not been well-characterized in ganglion cells. METHODS. Acute optic nerve crush was used to examine neuron...

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Detalhes bibliográficos
Main Authors: Janssen, Katherine T., Mac Nair, Caitlin E., Dietz, Joel A., Schlamp, Cassandra L., Nickells, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626519/
https://ncbi.nlm.nih.gov/pubmed/23422829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-9310
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