Sclerostin alters serum vitamin D metabolite and fibroblast growth factor 23 concentrations and the urinary excretion of calcium

Inactivating mutations of the SOST (sclerostin) gene are associated with overgrowth and sclerosis of the skeleton. To determine mechanisms by which increased amounts of calcium and phosphorus are accreted to enable enhanced bone mineralization in the absence of sclerostin, we measured concentrations...

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Autori principali: Ryan, Zachary C., Ketha, Hemamalini, McNulty, Melissa S., McGee-Lawrence, Meghan, Craig, Theodore A., Grande, Joseph P., Westendorf, Jennifer J., Singh, Ravinder J., Kumar, Rajiv
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625358/
https://ncbi.nlm.nih.gov/pubmed/23530237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221255110
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