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Sclerostin alters serum vitamin D metabolite and fibroblast growth factor 23 concentrations and the urinary excretion of calcium

Inactivating mutations of the SOST (sclerostin) gene are associated with overgrowth and sclerosis of the skeleton. To determine mechanisms by which increased amounts of calcium and phosphorus are accreted to enable enhanced bone mineralization in the absence of sclerostin, we measured concentrations...

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Detalhes bibliográficos
Main Authors: Ryan, Zachary C., Ketha, Hemamalini, McNulty, Melissa S., McGee-Lawrence, Meghan, Craig, Theodore A., Grande, Joseph P., Westendorf, Jennifer J., Singh, Ravinder J., Kumar, Rajiv
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625358/
https://ncbi.nlm.nih.gov/pubmed/23530237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221255110
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