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Hypoxia induces a phase transition within a kinase signaling network in cancer cells
Hypoxia is a near-universal feature of cancer, promoting glycolysis, cellular proliferation, and angiogenesis. The molecular mechanisms of hypoxic signaling have been intensively studied, but the impact of changes in oxygen partial pressure (pO(2)) on the state of signaling networks is less clear. I...
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Autores principales: | , , , , , , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
National Academy of Sciences
2013
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3625329/ https://ncbi.nlm.nih.gov/pubmed/23530221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1303060110 |
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