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RNA transcription modulates phase transition-driven nuclear body assembly

Nuclear bodies are RNA and protein-rich, membraneless organelles that play important roles in gene regulation. The largest and most well-known nuclear body is the nucleolus, an organelle whose primary function in ribosome biogenesis makes it key for cell growth and size homeostasis. The nucleolus an...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Berry, Joel, Weber, Stephanie C., Vaidya, Nilesh, Haataja, Mikko, Brangwynne, Clifford P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586886/
https://ncbi.nlm.nih.gov/pubmed/26351690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1509317112
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