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Nuclear bodies: The emerging biophysics of nucleoplasmic phases

The cell nucleus contains a large number of membrane-less bodies that play important roles in the spatiotemporal regulation of gene expression. Recent work suggests that low complexity/disordered protein motifs and repetitive binding domains drive assembly of droplets of nuclear RNA/protein by promo...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Curr Opin Cell Biol
Main Authors: Zhu, Lian, Brangwynne, Clifford P.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562147/
https://ncbi.nlm.nih.gov/pubmed/25942753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2015.04.003
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