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Spatiotemporal control of intracellular phase transitions using light-activated optoDroplets

Phase transitions driven by intrinsically disordered protein regions (IDRs) have emerged as a ubiquitous mechanism for assembling liquid-like RNA/protein (RNP) bodies and other membrane-less organelles. However, a lack of tools to control intracellular phase transitions limits our ability to underst...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Shin, Yongdae, Berry, Joel, Pannucci, Nicole, Haataja, Mikko P., Toettcher, Jared E., Brangwynne, Clifford P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562165/
https://ncbi.nlm.nih.gov/pubmed/28041848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.11.054
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